A hard-hitting and timely report on a pervasive threat.
Deadly germs escape from advanced laboratories with alarming and perhaps catastrophic consequences, according to this sobering nonfiction book.
Investigative journalist Young, who’s worked as a reporter and editor for such outlets as USA Today, the Detroit Free Press, and the Atlanta Journal-Constitution, explores lapses, accidents, and disasters at high-containment Biosafety Level 2, 3, and 4 laboratories around the world. They include a 1978 smallpox outbreak at a lab at Britain’s Birmingham University that resulted in the world’s last smallpox death (in which the remorseful lab director committed suicide); a 1979 anthrax release from a Soviet bioweapons lab in Sverdlovsk, which killed dozens of people; several leaks of contaminated wastewater at the U.S. Army’s Fort Detrick biological research institute in 2018, which may have traveled to the nearby town of Frederick, Maryland; a lab tech’s death from a bacterial infection in a San Francisco Veterans Administration medical center; several leaks of a SARS-associate coronavirus from Asian labs in 2003 and 2004, resulting in one death; and the exposure of lab workers to engineered microbes during “gain of function” research that seeks to make pathogens more infectious. A lengthy chapter explores the possibility that the Covid-19 pandemic was caused by a virus that escaped from the Wuhan Institute of Virology. Young dives deeply into how lab safeguards can fail because of equipment breakdowns, leaky pipes, holes in biohazard suits, mislabeled vials, accidental needle sticks, and other circumstances. The book also offers an absorbing account of Young’s own dogged reporting as she visits labs (she once found a high-tech containment-lab door sealed shut with duct tape), pries information out of reluctant officials, and receives tips from anonymous sources. She renders scientific issues in lucid, accessible prose that vividly conveys the insidious nature of potentially lethal microbes: “Other liquid or solid particles were so small they became airborne, spreading on invisible air currents, pushed along by heating and cooling systems, the opening and closing of doors, and the movement of people between rooms and down hallways.” Throughout, Young shows just how perilous infectious-disease research can be.
A hard-hitting and timely report on a pervasive threat.Pub Date: April 25, 2023
ISBN: 9781546002932
Page Count: 352
Publisher: Center Street/Hachette
Review Posted Online: Sept. 22, 2023
Kirkus Reviews Issue: Nov. 1, 2023
Review Program: Kirkus Indie
BOOK REVIEW
PERSPECTIVES
A powerful reiteration of principles—and some fresh ideas—from the longest-serving independent in congressional history.
Another chapter in a long fight against inequality.
Building on his Fighting Oligarchy tour, which this year drew 280,000 people to rallies in red and blue states, Sanders amplifies his enduring campaign for economic fairness. The Vermont senator offers well-timed advice for combating corruption and issues a robust plea for national soul-searching. His argument rests on alarming data on the widening wealth gap’s impact on democracy. Bolstered by a 2010 Supreme Court decision that removed campaign finance limits, “100 billionaire families spent $2.6 billion” on 2024 elections. Sanders focuses on the Trump administration and congressional Republicans, describing their enactment of the “Big Beautiful Bill,” with its $1 trillion in tax breaks for the richest Americans and big social safety net cuts, as the “largest transfer of wealth” in living memory. But as is his custom, he spreads the blame, dinging Democrats for courting wealthy donors while ignoring the “needs and suffering” of the working class. “Trump filled the political vacuum that the Democrats created,” he writes, a resonant diagnosis. Urging readers not to surrender to despair, Sanders offers numerous legislative proposals. These would empower labor unions, cut the workweek to 32 hours, regulate campaign spending, reduce gerrymandering, and automatically register 18-year-olds to vote. Grassroots supporters can help by running for local office, volunteering with a campaign, and asking educators how to help support public schools. Meanwhile, Sanders asks us “to question the fundamental moral values that underlie” a system that enables “the top 1 percent” to “own more wealth than the bottom 93 percent.” Though his prose sometimes reads like a transcribed speech with built-in applause lines, Sanders’ ideas are specific, clear, and commonsensical. And because it echoes previous statements, his call for collective introspection lands as genuine.
A powerful reiteration of principles—and some fresh ideas—from the longest-serving independent in congressional history.Pub Date: Oct. 21, 2025
ISBN: 9798217089161
Page Count: 160
Publisher: Crown
Review Posted Online: Oct. 21, 2025
Kirkus Reviews Issue: Dec. 15, 2025
BOOK REVIEW
BOOK REVIEW
BOOK REVIEW
A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular...
A neurosurgeon with a passion for literature tragically finds his perfect subject after his diagnosis of terminal lung cancer.
Writing isn’t brain surgery, but it’s rare when someone adept at the latter is also so accomplished at the former. Searching for meaning and purpose in his life, Kalanithi pursued a doctorate in literature and had felt certain that he wouldn’t enter the field of medicine, in which his father and other members of his family excelled. “But I couldn’t let go of the question,” he writes, after realizing that his goals “didn’t quite fit in an English department.” “Where did biology, morality, literature and philosophy intersect?” So he decided to set aside his doctoral dissertation and belatedly prepare for medical school, which “would allow me a chance to find answers that are not in books, to find a different sort of sublime, to forge relationships with the suffering, and to keep following the question of what makes human life meaningful, even in the face of death and decay.” The author’s empathy undoubtedly made him an exceptional doctor, and the precision of his prose—as well as the moral purpose underscoring it—suggests that he could have written a good book on any subject he chose. Part of what makes this book so essential is the fact that it was written under a death sentence following the diagnosis that upended his life, just as he was preparing to end his residency and attract offers at the top of his profession. Kalanithi learned he might have 10 years to live or perhaps five. Should he return to neurosurgery (he could and did), or should he write (he also did)? Should he and his wife have a baby? They did, eight months before he died, which was less than two years after the original diagnosis. “The fact of death is unsettling,” he understates. “Yet there is no other way to live.”
A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular clarity.Pub Date: Jan. 19, 2016
ISBN: 978-0-8129-8840-6
Page Count: 248
Publisher: Random House
Review Posted Online: Sept. 29, 2015
Kirkus Reviews Issue: Oct. 15, 2015
PERSPECTIVES
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