SEEDS OF DISCOVERY

A winning profile of a stubbornly self-motivated researcher who, through decades of study, revolutionized our understanding of genetics.

Acclaimed (eventually) by the Nobel Prize Committee for making “one of the two great discoveries of our times in genetics” (the other was the structure of DNA, discovered by others), Barbara McClintock was the very model of a maverick scientist. “It begins,” Alexander writes, “with a girl who loves science,” studies biology and plays jazz banjo in college, exchanges dresses for more practical trousers, and goes on to parlay an early fascination with the chromosomes found in corn cells into a lifelong study that culminates in finding the “jumping genes” (“transposons”) that play vital roles in genetic variance between generations. The author explains McClintock’s achievements in clear, nontechnical language and, after acknowledging her death at age 90 in 1992, goes on to highlight some of the advances, from the Human Genome Project to the development of CRISPR technology, that have resulted from her work. Along with close-ups of corn and chromosomes, Santo offers gracefully composed views of McClintock addressing colleagues and welcoming racially diverse groups of students to join her for tea and brownies. Most often, however, she’s in solitary absorption, hard at work in labs and cornfields. What will remain with readers is a memorable picture of an independent woman’s life in science, as well as a clear understanding of her contributions and a vivid sense of the joy she took in making them.

Absorbing and inspirational.